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March 8, 2007

Anti-obesity drugs to lead to cancer cure?

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It could happen, though a lot of research has yet to be done. According to the Wake Forest University Medical Center,

An approved drug for fighting obesity is helping scientists at Wake Forest University School of Medicine uncover clues about how to stop the growth of cancerous tumors. …

In the current issue of Cancer Research, [Steven J. ] Kridel [Ph.D] and colleagues are the first to report that a tubular network within cells, known as the endoplasmic reticulum (ER), is regulated by an enzyme that is tightly linked to tumor growth and development.

“When the ER cannot do its job properly, there’s a series of events that gets turned on that can lead to cell suicide or death,” said Kridel.

The research showed that an enzyme known as fatty acid synthase is vital for the ER to do its job. Blocking this enzyme, which makes fat in cells, has been shown to prevent tumor cell growth and to promote cell death.

“No one had made connection before between fatty acid synthase and the function of the ER in tumor cells,” said Kridel. “This is the first to show that fatty acid synthesis is important in maintaining ER function and keeping tumor cells alive.”

So, apparently, the same enzyme system that can (hopefully) be manipulated into killing fat cells can be manipulated into killing cancer cells. Serendipity knows no bounds.


Posted @ 5:12 pm. Filed under Nature and Science

Saudi women stepping up

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To combat female jihadists. Reports Crossroads Arabia,

They are playing a part in the overall efforts of the Saudi government to discourage youths from adopting extremist ideologies, nipping the problem in the bud rather than having to fight them in the streets. The article points to the way Al-Qaeda has paid attention to women in its own outreach programs and how female extremists are more difficult to pull away from their ideologies.

See what you think.


Posted @ 11:11 am. Filed under War on terror, Arab countries, Islam

What if Holland wars against Venezuela?

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Venezuelan dictator Hugo Chavez has been making noises about “Greater Venezuela,” meaning taking control of the south Caribbean islands of Dutch West Indies, lying near Venezuela’s coast.

What if the nutcase running Venezuela actually made a grab for the islands? Is it farfetched to anticipate? Venezuela’s economy is in the pits, wrecked by Chavez-flavored socialism. Hearken back to 1982, when Argentina was headed by a military junta, controlled by General Leopoldo Galtieri. Faced with economic crisis and growing opposition to the regime, Galtieri launched an invasion of the British territory of the Falkland Islands, about 400 km east of the country. Argentines have long considered the Falklands actually to be Argentine territory, las islas Malvinas, and Galtieri played on this sentiment in invading.

Could something like that be running through Chavez’s head? Like Britain of today, but unlike Britain of 1982, Holland has practically no power-projection capability. There is a modest Dutch military force stationed in the Dutch West Indies, but it would quickly be outmatched by Venezuela’s military.

In 1982, Britain sent a naval task force of two aircraft carriers, submarines and surface combatants to retake the Falklands. Other vessels brought Royal Marines and British Army troops. It was a bitter, hard-fought struggle and the British suffered significant losses, especially from Argie air power. However, the conscripts of the Argentine army in the Falklands were no match in the end for the Brits and the islands were returned to British control.

So what if Chavez moves against the DWI? Strategy Page analyzes the situation.


Posted @ 9:55 am. Filed under Foreign Affairs, Military, Europe & NATO
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